“The take home message is that INP104 is delivering DHE to the upper nasal space and it’s reflecting similar serum plasma levels at 20 minutes as the IV formulation but is also shown to be very tolerable.” Data from the phase 3, open-label STOP 301 study (NCT03557333) suggest that the novel nasal delivery system of […]
Summary: Following a potentially life-threatening event, people often report seeing their “lives flashing before their eyes”, where a multitude of memories from life events are recalled almost instantaneously. Researchers present theories on why this phenomenon may occur. Source: The Conversation At the age of 16, when Tony Kofi was an apprentice builder living in Nottingham, […]
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Data from the solriamfetol titration & administration (START) study presented at the 2021 SLEEP Virtual Annual Meeting, June 10-13, suggest that solriamfetol (Sunosi; Jazz Pharmaceuticals) is efficacious in patients switching narcolepsy medications and is easily titrated for these individuals.1 “Pharmacotherapy for excessive daytime sleepiness (EDS) associated with narcolepsy is diverse, with factors such as efficacy, […]
Tinnitus, sometimes called “ringing in the ears,” involves hearing a sound that cannot be linked to an external stimulus. In this video, I discuss nervous system mechanisms that might underlie tinnitus. Source link
Summary: Researchers say people continue to process music, even when no songs are playing. This can lead to earworms, or tunes that get stuck in your head, which can crop up during sleep. People who experience earworms regularly at night are six times more likely to report poorer quality sleep. Source: Baylor College of Medicine […]
Last night, we celebrated the graduation of our amazing and talented Chief Residents – Brian Gill, MD and Dominique Higgins, MD, PhD as they move onto individual fellowships in Neuro-Oncology: Dr. Gill, at Memorial Sloan Kettering and Dr. Higgins at the University of Miami. It is always hard to say goodbye, but we will cherish […]
Data from a recent study suggest that rimegepant (Nurtec ODT; Biohaven) achieves sustained migraine prevention within the first week of every other day dosing. These findings were presented at the 2021 Virtual American Headache Society (AHS) 63rd Annual Scientific Meeting, June 3-6, by Richard Lipton, MD, director, Montefiore Headache Center. “The benefits of oral preventive […]
Summary: Sleep disruptions have been linked to a higher risk of death, especially in those with type 2 diabetes. Researchers found those with type 2 diabetes who reported frequent sleep disruptions, were 87% more likely to die of any cause than those without diabetes or sleep disturbances. Additionally, those with diabetes and sleep disruptions were […]
“If you had 4 bad days a month, you’re missing 6 weeks of productive activity in a year. If you got up to 8, you’re missing 12 weeks out of the year. That’s a lot of time. There’s a cost that comes with that.” Andrew Blumenfeld, MD, and colleagues recently conducted research that evaluated the […]